17 results
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... • Evolution: ... life-threatening • Treatment ... management of SLE • Evolution ... comparison #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... of SLE versus DIL ... life-threatening • Treatment ... management of SLE • Evolution ... Management #Summary #rheumatology
Management of Lupus Nephritis
Lupus nephritis (LN) in 10 to 40% of SLE
Hallmark = proteinuria 20.5 g/g
Management of Lupus ... Nephritis Lupus ... renal histological evaluation ... Nephritis #Management #treatment ... #management #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... constitutional symptoms • Treatment ... • Evolution: ... #DIL #rheumatology ... #diagnosis #treatment
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
disease • Systemic lupus ... SJIA], systemic lupus ... Treatment: • Corticosteroids ... Diagnosis #Management #Hematology ... #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
MAS, Visceral, DIC ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
inhibitor and lupus ... Willebrand syndrome • Lupus ... administration, evaluation ... The appropriate evaluations ... Differential #Diagnosis #Hematology
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
Management Checklist Evaluation ... in cardiogenic pulmonary ... hypoperfusion, no pulmonary ... Revascularization, treatment ... #HeartFailure #Cardiology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Fibrinogen level, ↑ sIL ... Unknown cause Treatment ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
Esophageal Variceal Bleeding - Diagnosis and Management Summary
PRE-ENDOSCOPY
Vasoactive agents - Octreotide: 
 • 50mcg bolus →
Goal Hgb 7-9 g/dL ... TIPS • Pre-TIPS evaluation ... Diagnosis #Management #treatment ... endoscopy #varices #hepatology