20 results
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
integrity (trauma, infection ... commonly renal and pulmonary ... #Diagnosis #Dermatology ... #Differential #Ddxof
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
during medical evaluation ... drug reaction, infection ... Strongyloides infection ... glucocorticoid treatment ... Differential #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Triggering factor (infection ... Unknown cause Treatment ... inhibitors under evaluation ... diagnosis #management #treatment ... #summary #rheumatology
Tachypnea - Differential Diagnosis Framework

Definitions
 • Tachypnea: Respiratory rate > 20/min, shallow breathing in adults
 •
deep breathing Pulmonary ... Pneumonia • CHF ... Tachypnea: • Pulmonary ... effusion/Tamponade Hematologic ... dysfunction; toxic ingestions
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... Differential Diagnosis: Infection ... sepsis), PE, DAH, CHF ... diagnosis #management #hematology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... : Age>60, CKD, CHF ... , and CXR with pulmonary ... : No • Treatment ... Transfusion #Reactions #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
presentation, temporal evolution ... , CSF, and radiographic ... Antimicrobial treatment ... hemorrhage • CSF ... comparable to CSF
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Diaqnoses: • Infectious ... hepatitis • Pulmonary ... diagnosis #management #treatment ... #rheumatology
Severe Heart Failure & Cardiogenic Shock - Management Checklist 
Evaluation 
 - EKG & echocardiography
Management Checklist Evaluation ... in cardiogenic pulmonary ... hypoperfusion, no pulmonary ... Revascularization, treatment ... #Checklist #CHF
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
lesions (b) • CSF ... OCBs (30-70%) • Evolution ... corticosteroids TREATMENT ... Diagnosis #Management #treatment ... #rheumatology #