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management rheumatology sle dermatology druginduced summary syndrome systemic activation alopecia cerebritis cns comparison differential dil hair hairloss hemophagocytic hemophilia hlh
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... (SLE) - Diagnosis ... Positive in 60-80% of cases ... life-threatening • Treatment ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus ( ... autoantibodies that will cause ... permeability Diagnosis ... #Erythematosus ... #cerebritis #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... Erythematosus ( ... life-threatening • Treatment ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
+ Etiological Assessment ... for etiological assessment ... Treatment: • ... inhibitors under evaluation ... #management #treatment
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
normal in mild cases ... Avoid meds that ... though safety assessment ... #Management #treatment ... #hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Disease: Discoid lupus ... erythematosus, ... erythematosus, ... • Laboratory evaluation
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... erythematosus [ ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Sweet Syndrome Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Causes: - Idiopathic ... , breast CA - Hematologic ... ’s syndrome - Lupus ... Treatment: - Systemic ... Sweet #Syndrome #diagnosis
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
constitutional symptoms • Treatment ... Discontinuation of causal ... cutaneous-DIL • Evolution ... #DIL #rheumatology ... #diagnosis #treatment
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