35 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... ) 30-45% Differential ... autoantibodies #signs ... #rheumatology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... present, symptoms, signs ... transformation into AML ... von Willebrand disease ... #treatment #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... #diagnosis #management ... #hematology #oncology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's Disease ... fraction < 20% Differential ... Diaqnoses: • ... #diagnosis #management ... #treatment #rheumatology
Hyperviscosity Syndrome - Causes and Treatment

 - Waldenstrom macroglobulinemia (most common) / Plasmapheresis 
 - Multiple
Syndrome - Causes and Treatment ... hyperleukocytosis (AML ... Syndrome #Causes #Differential ... #Diagnosis #Treatment ... #Management
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... to be present Treatment ... target to 3-4 • DOACs ... #management #anticoagulation
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
Willebrand Syndrome - Diagnosis ... and Management ... thrombocythemia), Autoimmune disease ... #Management #treatment ... #hematology #differential
Optic Neuritis - Diagnosis and Management
 • Epidemiology: Female (75%), 18-50 years,
caucasian
 • Symptoms: Moderate visual
and Management ... Unilateral • Signs ... other auto-immune diseases ... #Management #treatment ... #rheumatology #
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... D/c all heparin ... , Bivalirudin, DOAC ... #Management #Treatment ... #Hematology #HemeOnc
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
artery aneurysms Diagnosis ... ) Differential Diagnosis ... Arthritis, AS Treatment ... #management #signs ... #symptoms #rheumatology