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differential rheumatology oncology causes treatment algorithm hemophagocytic hlh leukemia lymphohistiocytosis syndrome workup classification dermatomyositis hemeonc hepatology immunology lymphocytic thrombocytopenia abg
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
and Differential Diagnosis ... - CD7, CD3 Chronic ... • Lymphoid (CLL ... CD23, o CML ... #hematology #Markers
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... extramedullary disease ... involvement CML ... #Leukemia #Hematology ... #Oncology #Diagnosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... Algorithm #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary ... Physical Exam/Signs ... cells can indicate disease ... lymphoproliferative disorders ... workup #oncology #hematology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Summary of Coagulation ... LMWH, warfarin, DOACs ... Malignancy, Autoimmune disorders ... table #comparison #diagnosis ... #hematology #deficiency
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
- Differential Diagnosis ... hemorrhage) • Chronic ... inflammatory disorders ... myeloid leukemia (CML ... #Causes #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
deficiency anemia, Chronic ... Unstable hemoglobin disorders ... myeloma Rouleaux: Chronic ... #differential #diagnosis ... #hematology #microscopy
Basophilia - Differential Diagnosis Framework Basophils < 1% of the total white blood cell count Basophils function similarly
Myeloproliferative Disorders ... : • Chronic myeloid ... leukemia (CML) ... Colitis and Crohn’s Disease ... #causes #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
- Summary Overview ... leukemia in adults • Disorder ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... changes), high MCV ... not required in all ... Causes #Workup #hematology
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