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hematology management differential leukemia chronic classification disorders hodgkins lymphocytic lymphoma thrombocytopenia treatment workup algorithm anemia aplastic apml causes comparison differentiation
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... ALL Symptoms: ... ) CLL Symptoms: ... #Leukemia #Hematology ... #Oncology #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... Diagnosis: • ... #workup #oncology ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Differential Diagnosis ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Aplastic Anemia - Illness Script Signs and symptoms: • Recurrent infections from neutropenia • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... Symptomatic anemia Diagnosis ... Consider stem cell ... Can progress to MDS
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
minimal tumor burden Diagnosis ... Lauren Banaszak, MD ... uw_IMresidency #CLL ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
- Differential Diagnosis ... pattern of spread, B symptoms ... - Amy Chung, MD ... Classification #pathophysiology ... #Hematology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... • Induce blast cell ... : >3 symptoms, or ... #management #hematology ... #oncology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... Low or absent NK cell ... Ferritin >500 ng/mL ... management #treatment #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... Infection exposure (l MD ... pylori test (GI symptoms ... changes), high MCV ... not required in all
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes (MDS ... age 70 years Symptoms ... Myelogenous Leukemia (CML ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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