23 results
Algorithm for Investigation of Abnormal Coagulation Tests
- Prolonged PT
- Prolonged aPTT and Prolonged PT
- Prolonged aPTT

Dr.
Investigation of Abnormal Coagulation ... #Algorithm #Coagulation ... APTT #Laboratory #Hematology ... #Diagnosis #Workup
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
Summary of Coagulation ... LMWH, warfarin, DOACs ... RA, SLE), Post-partum ... table #comparison #diagnosis ... #hematology #deficiency
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... Splenomegaly - CTD (SLE ... Associated - SLE ... #hematology #rheumatology ... #nonpalpable #dermatology
Thromboelastogram Interpretation
Reaction Time (R Value):
 - Time till initiation of fibrin clot
 - Treatment: FFP, protamine
K
minutes after MA/MCF ... Thromboelastography #diagnosis ... #coagulation #hematology
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
evaluation or workup ... 1,500 cells/µL Workup ... organ-specific signs ... #Differential #diagnosis ... #hematology #eosinophilia
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... test, ANA (e.g., SLE ... changes), high MCV ... #hematology
Causes of Anemia with Normal Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased WBCs
 - Decreased/NormaI
Corpuscular Volume (MCV ... - Differential Diagnosis ... RA, SLE, PRV, Chronic ... #Differential #Diagnosis ... Algorithm #Causes #Hematology
Thrombotic Microangiopathy - TMAs
1. Not all MAHAs are due to TMAs but (almost) all TMAs cause
metabolism and coagulation-mediated ... catastrophic APS, SRC, SLE ... Microangiopathy #TMAs #hematology ... #diagnosis #ttp
Anemia Diagnostic Algorithm

Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
Anemia Diagnostic ... (cell) volume (MCV ... Anemia #Algorithm #Diagnosis ... #Workup #Hematology
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
- Differential Diagnosis ... genotypes): SS, SC, SE ... #Differential #Diagnosis ... #Algorithm #workup ... #hematology #testing