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differential antibody nuclear patterns testing vasculitis allergy anca antibodies antineutrophil chronic classification cll cytoplasmic dermatology disease diseases erythematosus immunology lupus
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
lymphocytic lymphoma (SLL ... Lymphocytic Lymphoma (SLL ... transformation of the CLL/SLL ... #Hematology #Oncology ... #Diagnosis
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns Nuclear Patterns: • Homogeneous pattern: -
Antinuclear Antibody ... Smith, Sm/RNP, Scl ... #Antinuclear #Antibody ... #differential #diagnosis ... #rheumatology
ANA (Antinuclear Antibody) and ANCA (Antineutrophil cytoplasmic antibodies) • Systemic lupus erythematosus 1. Anti-dsDNA
ANA (Antinuclear ... in drug-induced SLE ... scleroderma) - Anti-Scl ... #antibodies #diagnosis ... #rheumatology #
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Oral aphthae : SLE ... tears, Ischemia, Leukemia ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... #diagnosis #workup ... #oncology #hematology
Antinuclear Antibody Testing - Nuclear Patterns Homogeneous pattern: • SLE, SSc, AIH, JIA • dsDNA, chromatin,
Antinuclear Antibody ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... #differential #diagnosis ... #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Non-autoimmune rheumatologic ... La, anti-Jo-1, SCL ... leukemia • Lung ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
VASCULITIS: • Behçet ... purpura: strong sign ... LFT • ESR • ANA ... SLE) • Urinalysis ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... diseases, such as SLE ... purpura: Strong sign ... vasculitis • Behcet ... #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Chronic Myelogenous Leukemia ... (CML) • Felty ... • Hairy Cell Leukemia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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