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differential erythematosus lupus symptoms autoimmune management myositis vasculitis activation anteriorischemicopticneuropathy autoantibodies behcet classification disease gca giantcellarteritis hematology macrophage mas mimickers
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
effusion, Restrictive lung ... of hip (rare), Arthritis ... Demyelinating syndromes ... #signs #symptoms ... #diagnosis #rheumatology
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
of giant cell arteritis ... Doppler US : halo sign ... PET/CT: aortitis ... Ophthalmology #Diagnosis ... #Algorithm
Autoimmune Myositis Necrotizing myopathy is associated with higher CK levels, greater level of muscle weakness, less systemic
weakness, less systemic ... heliotrope rash, Shaw sign ... , holster sign, ... anti-synthetase syndrome ... #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... : - Arthritis ... Myositis 4% - Lung ... autoantibodies #signs ... #differential #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... Oral aphthae : SLE ... : SLE, Reactive ... #signs #symptoms ... #rheumatology #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
rash) • Heart, lung ... erythematosus [SLE ... 5000 to 10,000 ng/mL ... #Diagnosis #Management ... #Hematology #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Non-autoimmune rheumatologic ... syndrome Arthritis ... #Rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... • Cogan Syndrome ... purpura: strong sign ... vasculitis, and SLE ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... Vasculitis Differential Diagnosis ... diseases, such as SLE ... purpura: Strong sign ... #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
RP-ILD), dermato-rheumatologic ... papules and Gottron sign ... ) • Shawl sign ... • Nonerosive arthritis ... • Conduction system
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