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hematology treatment neurology cardiology lupus sle syndrome erythematosus pulmonary sclerosis adultonset algorithm aosd arthritis cardiomyopathy classification comparison dermatology hemophagocytic hlh
Diagnostic Schema for Hyperferritinemia Pearl: Diseases associated with extreme elevations: 1. HLH 2. Still's disease 3. Systemic
Diagnostic Schema ... Still's disease ... Systemic histoplasmosis ... Hyperferritinemia #Algorithm #Differential ... #Diagnosis #Hematology
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
fraction < 20% Differential ... solid cancers • Systemic ... #Disease #diagnosis ... #management #treatment ... #rheumatology
Manifestations of IgG4-related disease by organ system. The most common primary disease features are indicated in
of IgG4-related disease ... by organ system ... #Organs #Systems ... #Diagnosis #Hematology ... #Signs #Symptoms
Seronegative Inflammatory Arthritis - Differential Diagnosis • Seronegative Rheumatoid Arthritis • Infectious Arthritis: Viral, Bacterial,
Inflammatory Arthritis - Differential ... Diagnosis • Seronegative ... , Sarcoidosis, Still's ... #arthritides #Differential ... #Diagnosis #rheumatology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... Multiple sclerosis, Still's ... autoantibodies #signs ... #symptoms #mimickers ... rheumatology
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
autoimmune disease ... skin thickening Signs ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's ... Disease (AOSD) ... episode (30%) Systemic ... #rheumatology #diagnosis ... #management #treatment
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... • Homogeneous: Systemic ... ) • Speckled: Systemic ... ANA #patterns #rheumatology ... #diagnosis #differential
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... disease • Systemic ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
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