21 results
Antinuclear Antibodies (ANA)
ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
context of other symptoms ... : Lupus (SLE), Systemic ... Lymphoproliferative Disorders ... ANA #patterns #rheumatology ... #diagnosis #differential
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... Auto-Antibodies ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Lupus (SLE) General ... pain (20%) Renal disease ... Thrombocytopenia #Lupus #SLE ... #signs #symptoms ... #diagnosis #rheumatology
Summary of Coagulation Deficiencies
Inherited:
 • Hemophilia A - Deficiency of Factor VIII
 • Hemophilia B -
LMWH, warfarin, DOACs ... Malignancy, Autoimmune disorders ... RA, SLE), Post-partum ... Deficiencies #Summary #table ... #comparison #diagnosis
Antinuclear antibodies and Systemic lupus
Anti-dsDNA	60-80%	Association with disease activity (when with Farr assay) and lupus nephritis. Can
Antinuclear antibodies ... and Systemic lupus ... erythematosus #diagnosis ... #rheumatology # ... table #ANA
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... PT, aPTT(liver disease ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... anti-phospholipid antibodies
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
months to years) Systemic ... Evolution: Chronic disease ... #comparison #table ... #rheumatology # ... diagnosis #management
Features That Differentiate Acute Pericarditis from Myocardial Ischemia or Infarction and Pulmonary Embolism

In contrast to the
disorders, although ... presentation of systemic ... #Signs #Presentation ... #comparison #Table ... #Diagnosis
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology