16 results
Antinuclear Antibody Testing - Nuclear and Cytoplasmic Patterns
Nuclear Patterns:
 • Homogeneous pattern: 
   -
Antinuclear Antibody Testing ... pattern: - SLE ... Antinuclear #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... Positive Coombs testing ... younger pts) Differential ... Hemoglobinuria (PCH ... hemolytic #anemia #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
in HIV / AIDS - Differential ... should be based on clinical ... of serum CrAg testing ... comparable to CSF testing ... CNS #Infections #differential
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... genotypes): SS, SC, SE ... aHUS, mechanical cardiac ... #workup #hematology ... #testing
Antinuclear Antibody Testing - Nuclear Patterns
Homogeneous pattern: 
 • SLE, SSc, AIH, JIA
 • dsDNA, chromatin,
Antinuclear Antibody Testing ... Homogeneous pattern: • SLE ... pattern: • SjS, SLE ... Nuclear #Patterns #differential ... #diagnosis #rheumatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... smear, HIV/HCV testing ... pylori test (GI symptoms ... test, ANA (e.g., SLE ... #Workup #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Cytopenias • Cardiac ... Induced Lupus: • Symptoms ... #Rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Autoimmune diseases • Clinical ... - Pel-Ebstein ... Diagnosis of B-Symptoms ... #differential # ... hematology
Antinuclear Antibody Testing Cytoplasmic Patterns
Reticular/AMA: 
 • PBC, SSc, PBC/SSc OS, PBC/SjS OS
 • AMA
Speckled:
 •
Antinuclear Antibody Testing ... -7, PL-12, MDA5, ... Antinuclear #Antibody #Testing ... Cytoplasmic #Patterns #differential ... #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
thrombosis, VTE) • Cardiac ... Behcet disease) Differential ... Oral aphthae : SLE ... • Arthritis: SLE ... #rheumatology #