10 results
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Incidence, Symptoms ... , Complications ... and Treatment ... #Pharmacology # ... Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
minimal tumor burden Diagnosis ... thrombocytopenia Complications ... Lymphocytic #Leukemia #oncology ... hematology #hemeonc #diagnosis ... #management
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... : >3 symptoms, or ... fluid overload, PCC ... #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... tourniquet / IVF line draw ... line, stabilizes cardiac ... #Management #Treatment
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome • Diagnosis ... irrigation • Management ... • Bleeding • Cardiac ... Tolvaptan) • Treatment ... Diuresis #Nephrology #Pharmacology
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
its Chloride (Cl ... Hyperkalemia, a complication ... #criticalcare #management ... #diagnosis #treatment ... #pharmacology #
Monkeypox

What?
Monkeypox virus belongs to the family Poxviridae, subfamily Chordopoxvirinae, and genus orthopoxvirus
Viral zoonotic disease that is
chain reaction (PCR ... IgM antibody Complications ... Respiratory distress Treatment ... Monkeypox #MPOX #Diagnosis ... #Management #Dermatology
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
ethnicities Symptoms ... Multiple myeloma Complications ... vessel aneurysms • Cardiac ... affected tissue Treatment ... #management
Management of Anthracyclines and HER2 Antagonist Cardiotoxicity
Anthracyclines cause cardiomyopathy:
 ✖ Reduction in left ventricular ejection fraction
Management of Anthracyclines ... heart failure symptoms ... ) and initiate treatment ... Cardiotoxicity #cardiology #oncology ... #pharmacology #