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management rheumatology cardiology causes hematology pulmonary clinical disease infectiousdiseases neurology oncology pathophysiology aids algorithm aorta aorticdissection aorticflap apml arrhythmias arteritis
Kawasaki Disease (Mucocutaneous Lymph Node Syndrome) An rare systemic acute febrile vasculitic syndrome. Aetiology unknown. Affects
Early diagnosis ... prevent lethal cardiac ... complications. ... Disease #Features #Signs ... #Symptoms #Diagnosis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... WBC >100k, + lab signs ... lethargy, hematuria, cardiac ... with tetany or cardiac ... #TLS #diagnosis
Refeeding Syndrome Overview What Is It? • Electrolyte/fluid shifts caused by initiation of nutrition in severely malnourished patient.
severe clinical complications ... thiamine) Late: • Cardiac ... overload) Other Symptoms ... #Nutrition #Differential ... #Diagnosis #Pathophysiology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
with no early symptoms ... Physical Exam/Signs ... phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
life-threatening Differential ... Miller Fischer and PCB ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign
Cauda Equina Syndrome Overview Cauda Equina Syndrome: • Prevalence: 1:33,000-100,000 ppl/yr • Incidence: 1.5-3.4 million ppl/yr •
spine L1-L5 Symptoms ... Diagnosis: • ... axial T1 and T2 Treatment ... #differential # ... diagnosis #causes
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... Behcet disease) Differential ... Arthritis, AS Treatment ... #signs #symptoms
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... : • Triad of symptoms ... urine • Other symptoms ... HAGMA • Late complication
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... : >3 symptoms, or ... initiation • Differential ... fluid overload, PCC
Premature Ventricular Complexes (PVC's) - Summary Framework Why PVCs? Can be the first manifestation of cardiac
manifestation of cardiac ... (e.g., long QT syndrome ... Digoxin toxicity Symptoms ... fibrillation Complications ... more intensive treatment
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