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syndrome management apml chronic cll criteria dermatology dermatosis differentiation erythematosus febrile leukemia leukostasis lupus lymphocytic lysis mds myelodysplastic neutrophilic sle
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Syndrome (MD) - Diagnosis ... transformation to acute ... only curative treatment ... #Management #treatment ... #hematology #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology ... #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
- ACS, AKI, acute ... lethargy, hematuria, cardiac ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... ’s lymphoma or acute ... #workup #oncology ... #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... Sweet Syndrome (Acute ... Excellent response to treatment ... count >10 x 10^3/pL ... #Hematology #Dermatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Differential Diagnosis ... 5% of patients Cardiac ... Cytopenias • Cardiac ... #Rheumatology
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