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management syndrome hematology lysis tumor workup anesthesiology apml checklist chronic cll differentiation hyperkalemia intraoperative k leukemia leukostasis lymphocytic nephrology potassium
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS Laboratory TLS: • Uric
) and Treatment ... age and sex) • Cardiac ... hypocalcemia Treatment ... #diagnosis #management ... #oncology
Tumor Lysis Syndrome - Workup and Management Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
of the above Treatment ... of Clinical TLS ... abnormalities • Cardiac ... Lysis #Syndrome #diagnosis ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
leukapheresis - TLS ... with tetany or cardiac ... Lysis #Syndrome #TLS ... #diagnosis #management ... #hematology
Cardiac Tamponade - Guidelines for Crises in Anaesthesia Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... • Diagnostic ... thoracotomy is a better treatment ... • Prep and drape ... Anesthesiology #Anesthesia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology ... #oncology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Antibiotics (Bactrim, PCN ... Acidosis, Cell Lysis (TLS ... tourniquet / IVF line draw ... line, stabilizes cardiac
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... #workup #oncology ... #hematology
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