9 results
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Laboratory changes ... of the above Treatment ... abnormalities • Cardiac ... #Syndrome #diagnosis ... #management #oncology
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... age and sex) • Cardiac ... hydroxide • Hyperkalemia ... Syndrome #TLS #diagnosis ... #management #oncology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... lethargy, hematuria, cardiac ... hydration - Hyperkalemia ... with tetany or cardiac ... Syndrome #TLS #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Hyperkalemia - Diagnosis ... Acidosis, Cell Lysis ... reabsorption) Workup ... tourniquet / IVF line draw ... line, stabilizes cardiac
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
full infectious work-up ... days → add fungal work-up ... TLS (tumor-lysis ... plasmapheresis Hypercalcemia ... #HemeOnc #Diagnosis
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
Cardiac Tamponade ... thoracotomy is a better treatment ... • Prep and drape ... Anesthesiology #Anesthesia #Intraoperative ... #Management #Workup
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
dantrolene and cardiac ... with dantrolene Hyperkalaemia ... Anesthesiology #Anesthesia #Intraoperative ... #Checklist #Diagnosis ... #Management #Workup
Hypermagnesemia - Diagnosis and Management

Hypermagnesemia is a serum magnesium concentration > 2.6 mg/dL.
Symptoms include hyporeflexia, hypotension,
Hypermagnesemia - Diagnosis ... depression, and cardiac ... untreated), Tumor lysis ... hypocalciuric hypercalcemia ... reverse Mg-induced changes
The crusade against “Ab”Normal Saline continues.  This is a non-physiologic fluid that can harm our
whose positive charges ... ECF and ICF both work ... the ECF causes Hyperkalemia ... criticalcare #management #diagnosis ... #treatment #pharmacology