14 results
Classification of Tumor Lysis Syndrome (TLS) and Treatment of Metabolic Abnormalities of TLS
Laboratory TLS:
 • Uric
Classification of Tumor Lysis ... Syndrome (TLS) ... Calcium ≤ 7.0 mg/dL Clinical ... age and sex) • Cardiac ... #TLS #diagnosis
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
leukapheresis - TLS ... with tetany or cardiac ... #Syndrome #TLS ... #diagnosis #management ... #hematology
Tumor Lysis Syndrome - Workup and Management

Initial workup: BMP, Serum uric acid, LDH, Urine output, Consider
Tumor Lysis Syndrome ... of the above Treatment ... of Clinical TLS ... abnormalities • Cardiac ... Syndrome #diagnosis
Hyperkalemia - Diagnosis and Management - GrepMed Handbook

S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
Acidosis, Cell Lysis ... (TLS, rhabdo/crush ... tourniquet / IVF line draw ... acidosis), CK+LDH (lysis ... line, stabilizes cardiac
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... Generalized fatigue - ALS ... Miller Fischer and PCB ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis
Chagas Disease (American trypanosomiasis) - Diagnosis and Management Summary
Acute Chagas Disease (8-12 weeks):
 • Mild: Malaise,
Treatment: ... evidence of cardiac ... T.cruzi without clinical ... evidence of cardiac ... #Management #Microbiology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... thrombosis, VTE) • Cardiac ... (Clinical Dx). ... Arthritis, AS Treatment ... signs #symptoms #rheumatology
Summary of Oncologic Emergencies

Neutropenic fever:
- Fever + ANC < 500 → start cefepime ± vancomycin (if
antibiotics TLS ... (tumor-lysis syndrome ... ): - Hematologic ... low Ca - q8 h TLS ... Oncology #HemeOnc #Diagnosis
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... shunt (Type 2) Clinical ... left heart 3-6 cardiac ... ) on room air Treatment ... #treatment #hepatology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... phenomenon CLL Diagnosis ... microglobulin Treatment ... • Richter’s Syndrome ... workup #oncology #hematology