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erythematosus hematology syndrome systemic druginduced neurology activation anticoagulation antiphospholipid cerebritis chronic classification cll cns comparison cryoglobulinemia cryoglobulins dil gravis guidelines
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... 40, F:M 9:1 • Clinical ... life-threatening • Treatment ... #Management #Summary ... #rheumatology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
): • Lupus anticoagulant ... at least: • 1 clinical ... of 1 clinical event ... to be present Treatment ... #diagnosis #management
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE ... ) Clinical Manifestations ... (for secondary APS ... CNS #neurology #rheumatology ... #management #treatment
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
- Summary Antinuclear ... severe disease Treatment ... #Summary #diagnosis ... #rheumatology # ... management
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... 40, F:M 9:1 • Clinical ... Usual therapeutic management ... #table #rheumatology ... #diagnosis #management
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Summary A defect ... shunt (Type 2) Clinical ... ) on room air Treatment ... features - Complete ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
accumulation of clinical ... Assessment • Clinical ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
cytokines, such as ... erythematosus [SLE ... Treatment: • Corticosteroids ... Activation #Syndrome #Diagnosis ... #Management #Hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
rheumatoid arthritis, SLE ... Miller Fischer and PCB ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
Cryoglobulinemia Summary ... deposit of immune complexes ... Syndrome: • Clinical ... (e.g. systemic lupus ... classification #rheumatology
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