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Hypereosinophilia and Hypereosinophilic Syndrome

 • Secondary Hypereosinophilic Syndrome
 • Clinically Relevant HES Variants
 • When to
Clinically ... disorders • Diagnosis ... and Treatment Algorithm ... #HES #Hematology ... #management #algorithm
Acquired von Willebrand Syndrome - Diagnosis and Management
 • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
- Diagnosis and ... Management • ... #Diagnosis #Management ... #treatment #hematology ... #differential
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... initiation • Differential ... fluid overload, PCC ... #management #hematology
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
life-threatening Differential ... Miller Fischer and PCB ... myasthenia Diagnosis ... Myasthenia #Gravis #diagnosis ... #management #neurology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Still's Disease Clinical ... fraction < 20% Differential ... Diaqnoses: • ... #management #treatment ... #rheumatology
Susac Syndrome - Clinical Triad
 - Central nervous system dysfunction
 - Branch retinal artery occlusion
 -
Susac Syndrome - ... Clinical Triad ... arterioles - Treatment ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Erythematosus (SLE) Clinical ... Demyelinating Syndrome ... permeability Diagnosis ... CNS #neurology #rheumatology ... #management #treatment
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
Hyponatremia - Diagnosis ... hyponatremia is a complex ... demyelination syndrome ... #Diagnosis #Treatment ... #management #nephrology
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... at least: • 1 clinical ... presence of 1 clinical ... to be present Treatment ... #management #anticoagulation
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
binds heparin-PF4 complex ... : • Clinical Suspicion ... non-heparin A/C if clinical ... #Management #Treatment ... #Hematology #HemeOnc