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differential algorithm microscopy nephritic proteinuria renal causes glomerulonephritis syndrome testing workup atlas blood classification comparison diseases erythematosus hematuria initial interpretation
Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... Nephrotic Syndromes ... Nephritic syndrome—due ... RBC casts in urine ... #Diseases #Nephritic
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
/nephritic syndromes ... hematuria (RBC casts ... dysmorphic RBCs in urine ... #Algorithm #Nephrology ... #Diagnosis
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
- Diagnostic of ... glomerular disease ... ” - Necrotic tubular ... Microscopy #Atlas #key #diagnosis ... #nephrology #casts
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... syndrome ("Maltese ... Differential #Microscopy #Diagnosis ... #Nephrology
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
hemolytic-uremic syndrome ... cell/white cell casts ... urine sediment ... #nephrotic #syndrome ... #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #nephrology #interpretation ... #diagnosis
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
• Fanconi's syndrome ... • Drugs Glomerular ... sediment - WBC/RBC casts ... Minimal change disease ... #Proteinuria #Nephrology
Membranoproliferative Glomerulonephritis (MPGN) AKA: Mesangiocapillary GN • Active Urine Sediment (dysmorphic RBC, RBC casts, +/- proteinuria)
GN • Active Urine ... dysmorphic RBC, RBC casts ... formation along glomerular ... (Dense deposit disease ... #diagnosis #renal
Hematuria - Differential Diagnosis Framework Gross Hematuria: Red/Dark urine • 1ml blood/liter urine can induce color change
- Differential Diagnosis ... basement membrane disease ... hematuria: - RBC casts ... disease Renal ... causes #urology #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24- ... Spot PC (protein ... in monitoring low-level ... testing #workup #diagnosis ... #nephritic #nephrology
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