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differential management gitelman syndrome treatment workup algorithm alkalosis causes chloride defects diuresis diuretics epithelial hyperkalemia hypokalemia inherited k kidney medications
Metabolic Alkalosis - Urinary Chloride Algorithm Cl- responsive metabolic alkalosis • Kidney loss of Cl-
result of increased excretion ... sodium is typically ... of sodium and potassium ... #Algorithm #nephrology ... #differential #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells Renal glucosuria - Na+-dependent glucose cotransporter Cystinuria - Amino acid transporter Bartter
of epithelial sodium ... renal tubular acidosis ... Defects #Kidney #Nephrology ... #Diagnosis #Differential ... #Table
Normal Anion-Gap Acidosis (NAGMA) - Differential Diagnosis Framework and Workup NAGMA - Chem, ABG or VBG - Calculate Anion
- Differential Diagnosis ... • Impaired H+ secretion ... #Metabolic #NAGMA ... #Differential #Diagnosis ... #Workup #nephrology
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
• ↓ Renal K+ Excretion ... tourniquet / IVF line draw ... lysis) ± Urine ... Elimination (see Table ... Treatment #potassium #nephrology
Gitelman Syndrome - Diagnosis and Workup Blood Work: - Hypokalemia - Hypomagnesemia - Metabolic Alkalosis - Elevated
Hypomagnesemia - Metabolic ... Elevated Renin Urine ... - Fractional excretion ... of Cl > 0.5% Clinical ... #Workup #nephrology
Diuretics and Agents Regulating Renal Excretion Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide) • Glaucoma • Epilepsy • Altitude
Regulating Renal Excretion ... resistance • Metabolic ... disequilibrium syndrome • Diagnosis ... #Diuresis #Nephrology ... #Medications #Table
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
- Differential Diagnosis ... Heat stroke - Metabolic ... Weakness - Dark urine ... hour with goal urine ... causes #treatment #nephrology
Gitelman Syndrome Overview What? • Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter • Gitelman's syndrome
thiazide-sensitive sodium ... Hypocalciuria (spot urine ... Renal tubular acidosis ... Gitelman #Syndrome #diagnosis ... #nephrology #management
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