359 results
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... not initiate if eGFR ... not continue if eGFR ... #Metformin #Pharmacology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Cetuximab and other EGFR ... in Na-KATPase, EGFR ... Magnesium #Low #Causes
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
45-60 Monitor eGFR ... #Dosing #Dose #Pharmacology
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Dosing #Pain #Pharmacology
Drugs and Classes Associated with DILI and Type of Liver Injury

#Medications #Differential #DrugInduced #LiverInjury #Hepatology #Pharmacology
Drugs and Classes ... LiverInjury #Hepatology #Pharmacology ... #Causes #DILI
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
maximum dose eGFR ... recommended dose eGFR ... Metformin #CKD #pharmacology
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
#Medications #Pharmacology ... Impairment #CKD #Table #GFR
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... kidney function (eGFR ... Sterile pyuria, WBC casts ... Diagnosis #Algorithm #Causes
Hepatorenal Syndrome (HRS) - Diagnostic Criteria
HRS-AKI (Acute: previously known as HRS Type 1)
 • ↑ Creatinine
months - eGFR ... - No other cause ... HRS-CKD - eGFR ... - No other cause
Internal Jugular Vein Rouleaux Flow on POCUS

Amazing video of a dilated IJV showing Rouleaux flow. Whenever
Rouleaux Flow on POCUS ... significantly, it causes ... echogenic as in this case ... for underlying cause ... Jugular #IJ #Vein #POCUS