439 results
Interpreting Kidney Biomarkers

↑ Creatinine: 
 • AKI, CKD
 • Medications that lead to nephroprotective ↓ in
nephroprotective ↓ in GFR ... Medications that ↓ renal ... hyperthyroidism ↓ eGFR ... Biomarkers #Kidney #renal
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
recommendations in renal ... #Medications #Pharmacology ... Dosing #Dosing #Renal ... Impairment #CKD #Table #GFR
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
Metformin Current Renal ... 45-60 Monitor eGFR ... #Metformin #Renal ... #Dosing #Dose #Pharmacology
Renal Failure Prognosis - The eGFR and proteinuria offers a general prognosis as demonstrated in the
Renal Failure Prognosis ... - The eGFR and ... #CKD #EGFR #Proteinuria
Adjusted Pain Medication Dosing based on GFR

#Renal #Dosing #Pain #Pharmacology #Opiates #CKD #Gabapentin #Table
Dosing based on GFR ... #Renal #Dosing ... #Pain #Pharmacology
Causes of Hypomagnesemia - Differential Diagnosis Algorithm
GI LOSS - FeMg < 2-2.5% or 24h Urine Mg
Causes of Hypomagnesemia ... Malabsorption RENAL ... Cetuximab and other EGFR ... in Na-KATPase, EGFR ... Magnesium #Low #Causes
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
Causes of Chronic ... kidney function (eGFR ... 3 months Pre-Renal ... Atheroemboli • Renal ... hypoperfusion Post-Renal
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
Metformin Pharmacology ... agent • Does not cause ... not initiate if eGFR ... not continue if eGFR ... #Metformin #Pharmacology
To improve the usefulness of the serum creatinine concentration as a marker of kidney function, prediction
accurately predict GFR ... Modification of Diet in Renal ... unless a patient's renal ... seen in acute renal ... CockcroftGault #EGFR
Effects of Prostaglandins and NSAIDs on the Kidney
Effects of Prostaglandins on the Kidney:
 • The vasodilatory
importance in renal ... conditions of decreased renal ... production of renal ... NSAIDs #Kidney #renal ... #nephrology #pharmacology