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anemia algorithm management blood hemolytic reactions rheumatology atlas bloodcell cryofibrinogenemia dili elevatedmcv extravascular hodgkins injury intravascular lymphoma macrocytic macrocytosis mcv
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... (HUS) • Other ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
• Bleeding • Hemolysis ... (e.g. ... Renal Disease, Liver ... #Anemia #MCV #Classification ... #Causes #Hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... - Hemolytic ... deficiency • Liver ... #Diagnosis #hematology ... #nonpalpable #dermatology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... #Diagnosis #causes ... #classification ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
(e.g. methotrexate ... disease, Etc. ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
for alternative causes ... disease, Hepatic ... Hepatic vascular disorder ... hepatitis #DILI #DrugInduced ... #hepatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Causes #Hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
in recipient (e.g ... haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
haptoglobin, ↑LDH, etc ... eruptions, diarrhea, liver ... Occurs between 0-6 hrs ... #Transfusion #diagnosis ... #management #hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cryoglobulin (CG ... cryoglobulinemia Associated Disorders ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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