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algorithm anemia bleeding bruising mcv aptt coagulation comparison cryofibrinogenemia gap hemostasis hodgkins lymphoma macrocytic microcytic morphologic nonhodgkins oncology prolonged protein
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Myelodysplastic Syndromes ... Deficiency - Abnormal ... #elevatedMCV #Differential ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Synthesis or Decreased Globin ... HgbE, HgbC, etc. ... Microcytic #Anemia #Macrocytosis ... #elevatedMCV #Differential ... #Causes #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... (e.g. ... Renal Disease, Liver ... #Anemia #MCV #Classification ... #Causes #Hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Causes #Hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
: Alcohol use, Liver ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
the spleen or liver ... translocation • Types: Classification ... also arise in normal ... #differential # ... hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Reduced liver synthesis ... #diagnosis #differential ... #hematology #coagulation
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Cold insoluble globulin ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
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