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rheumatology activation algorithm bruising dermatology elevation hemolysis intravascular lactate lactic macrophage management mas mcv nonpalpable palpable pediatrics peds thrombocytopenia typea
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... thrombocytopenic purpura ... #Causes #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... Renal Disease, Liver ... #MCV #Classification ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... for Hemolytic Anemia ... : • Liver disease ... #Anemia #Differential ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... anemia - Splenomegaly ... deficiency • Liver ... Diagnosis #hematology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
Causes of Purpura ... - SLE (systemic ... Congenital heart disease ... peds #pediatrics #diagnosis ... #differential #
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
(eg, systemic juvenile ... with leukopenia, anemia ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
presentations and disease ... of Circulatory System ... - Compartment syndrome ... 30mmHg) - Severe anemia ... #Diagnosis #causes
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