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hemolytic algorithm agglutinin atlas autoimmune bloodcell cold elevatedmcv erythematosus gap globulin hemolysis hodgkins intravascular lupus macrocytic macrocytosis management mcv microscopy
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... . lupus, CLL, lymphoma ... #Causes #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... (e.g. ... #MCV #Classification ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... Diagnosis #causes ... #classification ... #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... IgM associated lymphoma ... , Malignant lymphoma ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
Ascites - Diagnostic ... most common causes ... (e.g. cirrhosis ... of underlying disease ... #Diagnosis #hepatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
) Classification ... Immunohistochemical studies (to differentiate ... of disease and ... #diagnosis #classification ... #hematology #oncology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cold Agglutinin Syndrome ... autoimmune disorder or lymphoid ... - Monoclonal - Lymphoid ... younger pts) Differential ... #hematology #diagnosis
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... . hematologic) ... lymphopenia, low PLT • Anemia ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia ... Gap #ProteinGap #differential ... #diagnosis #hematology
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