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management algorithm atlas morphology approach bleeding bloodcell bruising dic disorders disseminated elevatedmcv elevation extravascular gap globulin hemolysis hemolytic hemostasis hodgkins
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... coagulation (DIC ... • Intrinsic RBC ... #Causes #differential ... #diagnosis #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss ... • Acute Bleed - ... Disease • Marrow ... #Classification ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... (e.g. methotrexate ... , Liver disease, ... #Morphology #differential ... #diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Normal Blood Smear ... Myelodysplastic Syndromes ... #Causes #Hematology
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... , Liver diseases ... , Liver diseases ... #differential # ... hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
, Acute blood loss ... : Alcohol use, Liver ... Myelodysplastic syndrome ... #diagnosis #causes ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Hemolytic anemia ... deficiency • Liver ... - APLS • Acute ... #Diagnosis #hematology ... #nonpalpable #dermatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... plateletcount), peripheral blood ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
malignancy (Especially acute ... ABO incompatible blood ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Lactate Elevation, Lactic Acidosis - Differential Diagnosis The most common causes of hyperlactatemia are usually:
removal from the blood ... presentations and disease ... - Compartment syndrome ... 30mmHg) - Severe anemia ... #Diagnosis #causes
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