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algorithm oncology thrombocytosis anemia acidosis approach ascites bleeding bruising cll dili druginduced elevation erythematosus gap globulin hemostasis injury lactate lactic
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
Myelogenous Leukemia ... Infectious: • Acute ... disorders • Celiac disease ... effect following treatment ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... Myelodysplastic syndrome ... myeloid leukemia ... #Diagnosis #Causes ... #hematology #secondary
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... for workup, including ... Rebound effect from treatment ... • Infections: Chronic ... #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
Blood Loss • Acute ... Disease • Marrow ... Metabolism Disorder - Acquired ... Non-lmmune #Anemia #Classification ... #Causes #Hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... microglobulin Treatment ... or acute leukemia ... #diagnosis #workup ... #oncology #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Acute blood loss ... patients), "Hospital-acquired ... Myelodysplastic syndrome ... #diagnosis #causes ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Lymphoma Workup ... Immunohistochemical studies (to differentiate ... number of sites of disease ... Lymphoma Treatment ... #hematology #oncology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
non-essential drug/HDS treatments ... for alternative causes ... Alcohol-related liver disease ... dechallenge • Acute ... #Algorithm #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... (e.g. cirrhosis ... of underlying disease ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Diagnosis Framework ... gingivitis or gingival leukemic ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
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