ecg qtc syndrome acltear hematology disease differential classification causes hepatology rheumatology anemia diagnosis pulmonary workup deficiency macrocytic erythematosus gap

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Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology

Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
• Iron deficiency

Diagnostic Framework ... Myelodysplastic syndrome ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology

Red Blood Cell (RBC) Morphology Atlas
• Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning

Myelodysplastic syndrome ... , Pulmonary emboli ... Morphology #Atlas #key #diagnosis ... #differential # ... hematology

Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),

disease anemia ... (sometimes) Macrocytic ... Chemotherapy (e.g ... RBC #Morphology #differential ... #diagnosis #hematology

Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

Causes of Anemia ... Diagnosis Algorithm ... (e.g. ... #MCV #Classification ... #Causes #Hematology

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

Causes of Anemia ... (Eg Causes: Chronic ... HgbE, HgbC, etc. ... #Microcytic #Anemia ... #Causes #Hematology

Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
• Mechanical Trauma (Microangiopathic hemolytic anemia):

Diagnostic Framework ... G6PD deficiency) ... #differential # ... diagnosis #hematology ... #anemia

Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage

Purpura - Differential ... - Hemolytic anemia ... necrosis) • VIT K deficiency ... #Diagnosis #hematology ... #rheumatology #

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

Classification: ... permanent alopecia Differential ... • Prolidase deficiency ... lymphopenia, low PLT • Anemia ... #Diagnosis #Rheumatology

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

formed or don’t work ... common cytopenia: Macrocytic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology

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