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anemia algorithm coagulation management pt bruising disorders hemolytic mcv oncology pathophysiology treatment workup activation arterial atlas blood comparison cryofibrinogenemia dic
Causes of Prolonged PT (INR), Prolonged PTT • Prolonged PT (INR), Prolonged PTT • Prolonged PT
Causes of Prolonged ... PTT, Normal PT ... #PPT #PT #INR #Differential ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... hematology #coagulation
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... Destruction • Abnormal ... Iatrogenic) • Liver ... • Disseminated Intravascular ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... ) - HELLP syndrome ... #Causes #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
80-100 fL) • Bleeding ... (e.g. ... Renal Disease, Liver ... #Anemia #MCV #Classification ... #Causes #Hematology
Differential Diagnosis for a Prolonged PT and aPTT If the PT and the aPTT are both prolonged,
Differential Diagnosis ... • Reduced liver ... #PT #aPTT #Prolonged ... #Causes #diagnosis ... hematology #coagulation
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... Deficiency - Abnormal ... #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
PT/ABNORMAL PTT ... von Willebrand syndrome ... PT/ABNORMAL PTT ... discern these causes ... #Diagnosis #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
Thrombocytopenia • Prolonged ... DIC • Severe Liver ... Disease: - Impaired ... INR < 2.3 - APTT ... #management #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... disease), HBsAg ... #Diagnosis #Causes ... #Workup #hematology
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