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management algorithm activation anemia dic disorders disseminated hemophilia hemostasis macrophage mas mcv myelodysplasia myelodysplastic oncology platelet prolonged pt syndromes thrombocytopenia
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Destruction • Abnormal ... #Bleeding #Bruising ... #Causes #Hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
DIC • Severe Liver ... Disease: - Impaired ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... #Causes #diagnosis ... #differential # ... hematology #coagulation
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
80-100 fL) • Bleeding ... (e.g. ... Renal Disease, Liver ... #Anemia #MCV #Classification ... #Causes #Hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... PT/ABNORMAL PTT ... PT/ABNORMAL PTT ... discern these causes ... Diagnosis #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... disease), HBsAg ... #Diagnosis #Causes ... #Workup #hematology
Hemophilia - Diagnosis and Management Diagnosis: • Consistent bleeding history (unless screening for disease in family members
mixing study (aPTT ... mild cases) • ... hemophilia type (e.g ... Avoid meds that ... #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... thrombocytopenia • Liver ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... or bleeding, which ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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