17 results
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... uremic syndrome ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Corpuscular Volume (MCV ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... • Bleeding • Hemolysis ... (e.g. ... #Classification ... #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
- Differential ... Myeloproliferative disorders ... Serum Sickness Hemolytic ... Spleen #Enlarged #Differential ... #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
) - Differential ... HgbE, HgbC, etc. ... Microcytic #Anemia #Macrocytosis ... #elevatedMCV #Differential ... #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential ... function test, ANA (e.g ... changes), high MCV ... #Differential # ... #Workup #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Reticulocytes, MCV ... Anemia of Chronic Disease ... Non-lmmune #Anemia #Classification ... Diagnosis #Algorithm #Causes ... #Hematology
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... DIC/TTP/HUS - Hemolytic ... • HCV, HBV Not ... #Diagnosis #hematology ... #rheumatology #
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
iron deficiency, hemolysis ... Chronic inflammatory disorders ... (e.g. autoimmune ... Myelodysplastic syndrome ... #hematology #secondary
Red Blood Cell (RBC) Morphology
Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Chemotherapy (e.g ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... RBC #Morphology #differential ... #diagnosis #hematology