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activation algorithm aortitis autoimmune cryofibrinogenemia cryoglobulinemia cryoglobulins dermatologic dermatology gpa granulomatosis hemostasis lupus macrophage management mds myelodysplasia myelodysplastic myopathy myositis
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... • Steroids • Vasculitis ... #Bruising #Differential ... #Causes #Hematology
Aortitis - Differential Diagnosis Framework Non-Infectious Aortitis: • Vasculitides: Giant Cell Arteritis (GCA), Takayasu's arteritis, Cogan's Syndrome,
, Cogan's Syndrome ... (RA), Systemic ... lupus erythematosus ... Cancer, Histiocytic disorders ... #Diagnosis #rheumatology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... (e.g. systemic ... lupus erythematosus ... #types #classification ... #rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... (e.g. thyroid disease ... (NPSLE): • May ... #Diagnosis #Rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... manifestations: from easy bruising ... (eg, systemic juvenile ... #Diagnosis #Management ... #Hematology #Rheumatology
Causes of Purpura or Easy Bruising in Children Platelet count reduced, i.e. thrombocytopenia - Increased platelet destruction
- SLE (systemic ... lupus erythematosus ... Congenital heart disease ... pediatrics #diagnosis ... #differential #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
disease Differential ... Diagnosis: Systemic ... , such as systemic ... differential #diagnosis ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Diagnosis: Vasculitis ... • Goodpasture syndrome ... , extravascular ... #rheumatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... von Willebrand syndrome ... discern these causes ... integrity == • Vasculitis ... Diagnosis #Hematology
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Differential Diagnosis ... ischemia • Skin: Erythematous ... tract, and often causes ... Diagnosis #Rheumatology
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