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diagnosis anemia lymphadenopathy management comparison diffuse erythematosus extravascular focal hemolysis hemolytic intravascular leukemia localized lupus mcv mds myelodysplasia myelodysplastic myopathy
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
Hodgkin's Lymphoma ... Hodgkin's Lymphoma ... diseases (e.g., ... , Hodgkin Lymphomas ... #hematology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Age > 50 • Chronic ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
• Kikuchi Disease ... Tularemia • Secondary ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Immunosuppression • Autoimmune ... of cases) Classification ... Immunohistochemical studies (to differentiate ... number of sites of disease ... #hematology #oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Thalassemia • Lead ... Disease (e.g. ... #Anemia #MCV #Classification ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Extravascular Causes ... . lupus, CLL, lymphoma ... , Copper and lead ... #differential # ... diagnosis #hematology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
• Secondary form ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Malignancy Risk: • Non-Hodgkins ... #Rheumatology #
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... rheumatologic diseases ... with Lupus: • Chronic ... Erythematosus #Diagnosis #Rheumatology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... activity • ↓ LAP ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
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