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algorithm anemia lymphadenopathy vasculitis autoimmune cryoglobulinemia cryoglobulins dermatology diffuse extravascular focal hemolysis hemolytic intravascular leukemia localized lupus management mcv mds
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Systemic Lupus Erythematosus ... Age > 50 • Chronic ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
• Kikuchi Disease ... Tularemia • Secondary ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Thalassemia • Lead ... Disease (e.g. ... #Anemia #MCV #Classification ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... . hematologic) ... with Lupus: • Chronic ... #Diagnosis #Rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... . lupus, CLL, lymphoma ... #differential # ... diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... activity • ↓ LAP ... bone marrow and secondary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Type III Often Secondary ... systemic lupus erythematosus ... #types #classification ... #rheumatology #
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Eosinophilia, asthma, chronic ... tract, and often causes ... retinopathy Lab ... #diagnosis #rheumatology ... #classification
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
a rare chronic ... Rule out other causes ... Tetracyclines etc ... osteoarticular and skin disease ... #Rheumatology #
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #diagnosis #hematology ... #oncology
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