ecg qtc syndrome acltear hematology disease differential classification oncology algorithm anemia hepatology approach macrocytic causes syndromes mcv mds

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Algorithmic Approach to Anemia - Differential Diagnosis Framework by MCV

Microcytic (MCV < 80) "TAILS":
• Thalassemia

Algorithmic Approach ... to Anemia - Differential ... Non-megaloblastic: Liver disease ... #MCV #Algorithm ... Diagnosis #hematology

Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
• Iron deficiency

(Morphological Approach ... Myelodysplastic syndrome ... #differential # ... diagnosis #causes ... #hematology

Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
•

Causes of Anemia ... Corpuscular Volume (MCV ... ) - Differential ... Myelodysplastic Syndromes ... #Causes #Hematology

Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80

Causes of Anemia ... ) - Differential ... (e.g. ... #MCV #Classification ... #Causes #Hematology

Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
• Acute Bleed - Normocytic / Normochromic

to Anemia - Differential ... Reticulocytes, MCV ... #Classification ... #Approach #Differential ... #Causes #Hematology

Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or

Causes of Anemia ... ) - Differential ... HgbE, HgbC, etc. ... #Microcytic #Anemia ... #Causes #Hematology

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

Approach to Thrombocytosis ... → Refer to hematology ... hemolysis, deficiency anemia ... Kawasaki, Nephrotic syndrome ... #hematology

Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
• Infectious: Hepatitis C, A,

Causes of Acute ... E, B, D, EBV, CMV ... obstruction, HELLP Syndrome ... #Acute #algorithm ... #hepatology

Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly

common cytopenia: Macrocytic ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology

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