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anemia elevatedmcv macrocytosis management activation atlas blood classification disorders extravascular hemolysis hemolytic intravascular key lesions macrocytic macrophage mas mcv mds
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
Causes of Bleeding ... / Bruising - Differential ... Diagnosis Algorithm ... Rare • Drugs (e.g ... #Causes #Hematology
Causes of Thrombocytopenia - Differential Diagnosis Algorithm Decreased Megakaryopoiesis • Aplastic Anemia • Toxic Damage (e.g.
Causes of Thrombocytopenia ... Diagnosis Algorithm ... Toxic Damage (e.g ... Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Causes of Thrombocytopenia ... deficienies Labs: - Basic ... function test, ANA (e.g ... #Diagnosis #Causes ... #Workup #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Diagnosis Algorithm ... 80-100 fL) • Bleeding ... Chronic Disease (e.g ... #Diagnosis #Algorithm ... #Causes #Hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
(usually IgG) (e.g ... (usually IgM) (e.g ... deficiencies (e.g ... #differential # ... diagnosis #hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Decreased Heme Synthesis or
Diagnosis Algorithm ... Iron Deficiency (Eg ... Other • e.g ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
manifestations: from easy bruising ... underlying disease (eg ... • Infection (eg ... #Diagnosis #Management ... #Hematology #Rheumatology
Primary Dermatological Lesions Primary lesions are physical changes in the skin considered to be caused directly by
altered colour e.g ... nipple-like mass e.g ... bruise') is where bleeding ... nettle sting #Diagnosis ... #Dermatology #Skin
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... platelet count (thrombocytopenia ... IDUS) • Immune Thrombocytopenia ... blood count with differential ... #diagnosis #hematology
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