15 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Reactive arthritis,ervical ... Arthritis, AS Treatment ... azathioprine #Behcet ... #management #signs ... #symptoms #rheumatology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
: 33% • Treatment ... , and CXR with pulmonary ... edema) • Fever ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
disequilibrium syndrome ... Torsemide) • Acute pulmonary ... • Liddle syndrome ... Tolvaptan) • Treatment ... #Medications #Table
Rheumatoid Arthritis - Signs and Symptoms
 • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans
 • Pulmonary:
Rheumatoid Arthritis - Signs ... Scleromalacia perforans • Pulmonary ... Entrapment neuropathy, Cervical ... Thrombocytosis, Felty's syndrome ... Symptoms #diagnosis #rheumatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... myalgias, HoTN, edema ... Imaging: CXR- pulmonary ... diagnosis #management #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
progressing GN • New pulmonary ... VASCULITIS: • Behçet ... • Cogan Syndrome ... purpura: strong sign ... differential #diagnosis #rheumatology
Clarkson’s Disease - Capillary leak syndrome
Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... , compartment syndrome ... filling +++ (risk of pulmonary ... edema) Treatments ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
Overwhelming clinical syndrome ... age, however the disease ... Diagnosis: HLH signs ... • Bicytopenia Treatment ... #hematology
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
purpura: Strong sign ... vasculitis • Behcet ... syndrome: Recurrent ... vasculitis • Cogan syndrome ... Differential #Diagnosis #Rheumatology
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
trabecular and cortical ... and lower jaw Treatment ... osteoarticular and skin disease ... #Rheumatology # ... diagnosis #management #Dermatology