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diagnosis management hematology oncology signs disease classification inflammatory kawasaki leukemia treatment vasculitis acute algorithm allergy anaphylaxis ards arthritis associations autoantibodies
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... myalgias, HoTN, edema ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Leukemia #Hematology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... , others (RNP, aPL ... Antiphospholipid Antibody Syndrome ... LAC) • Sjogren Syndrome ... #associations #table
TRALI vs TACO - Transfusion Reactions TRALI: • Epidemiology: 0.1% of transfused patientsl • Risk factors: Critical
: ARDS Berlin Criteria ... ARDS to explain symptoms ... with pulmonary edema ... Transfusion #Reactions #hematology ... diagnosis #comparison #table
Gestational Hypertension & Preeclampsia Gestational Hypertension (gHTN) • BP > 140/90 • Onset > 20 wks gestation
• Pulmonary edema ... Cerebral/visual symptoms ... Seizure HELLP Syndrome ... Classification #Diagnosis #Criteria
Clinical manifestations of anaphylaxis. Neurological (<15%): Dizziness, syncope, seizures, Confusion, impending doom. headache Angioedema: Lips, tongue, orbit,
arrest, Kounis syndrome ... oropharyngeal edema ... <10%): Scrotal edema ... anaphylaxis #signs #symptoms ... #diagnosis #criteria
Berlin Criteria for Acute Respiratory Distress Syndrome (ARDS) - Respiratory symptoms must have begun within one
Berlin Criteria ... Respiratory Distress Syndrome ... - Respiratory symptoms ... new or worsening symptoms ... with pulmonary edema
Kawasaki Disease: Clinical Findings Diagnostic Criteria - Fever and 4/5 of the following: • Conjunctivitis • Polymorphous
Findings Diagnostic Criteria ... Polymorphous rash • Cervical ... involvement • Edema ... feet Signs/Symptoms ... - Unilateral Cervical
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
Summary Diagnostic Criteria ... When present, symptoms ... • "Vasomotor" symptoms ... transformation into AML ... Summary #treatment #hematology
Kawasaki Disease (KD) - Diagnosis and Management Summary Kawasaki Disease (KD) is the most common vasculitis of
Mucositis, Rash, Hand edema ... Diagnostic Criteria ... palms or soles, edema ... Cervical lymphadenopathy ... KD #vasculitis #rheumatology
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