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differential management myositis myopathies ophthalmology signs syndrome aion anteriorischemicopticneuropathy antibodies autoimmune behcet causes comparison cryofibrinogenemia cryoglobulinemia cryoglobulinemic dermatology diplopia disease
Myositis Specific Antibodies (MSAs) Dermatomyositis: MDA5, TIF1y, NXP2, Mi-2, SAE Anti-Synthetase Syndrome: Jo-1, PL7, PL12, EJ, OJ Immune Mediated
Mediated Necrotizing Myopathy ... ): HMGCR, SRP Inclusion ... Antibodies #MSAs #clinical ... #diagnosis #rheumatology
Myositis and Myopathies Polymyositis • Progressive, symmetric muscle weakness • Elevated CK, +Anti-Jo, +Anti-Mi2 Dermatomyositis
temporal arteritis Inclusion ... load Drug-induced myopathy ... 5-15% of lupus myopathy ... #differential #diagnosis ... #comparison #rheumatology
Idiopathic Inflammatory Myopathies (IIM's) RASH + MUSCLE WEAKNESS → Consider idiopathic inflammatory myopathies (IIM's) • Overlap Myositis
Any inflammatory myopathy ... antisynthetase syndrome • Inclusion ... Myopathies #IIMs #diagnosis ... #rheumatology # ... dermatology #Myopathy
Diagnosis of Cryoglobulinemia Vasculitis 1) Presence of cryoglobulin Circulating immunoglobulins that precipitate with cold temperature and dissolve
Diagnosis of Cryoglobulinemia ... not related to clinical ... l) : Vascular occlusion ... Cryoglobulinemia #Vasculitis #Diagnosis ... #Rheumatology #
Susac Syndrome - Clinical Triad - Central nervous system dysfunction - Branch retinal artery occlusion -
Susac Syndrome - Clinical ... retinal artery occlusion ... SusacSyndrome #Triad #Diagnosis ... #Management #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
and/or venous occlusions ... Cryofibrinogenemia Diagnosis ... tissue • Angio: Occlusion ... #rheumatology # ... hematology
Diplopia - Double Vision - Differential Diagnosis Algorithm Clinical Pearls: • Diplopia is almost always binocular. •
- Differential Diagnosis ... Algorithm Clinical ... of exclusion. ... Cataract/Lens Dislocation ... #Algorithm #Causes
Anterior ischemic optic neuropathy (AION) - Recognition of giant cell arteritis (GCA) 1) Is visual loss caused
altitudinal defect • Fundoscopy ... Clinical manifestations ... GiantCellArteritis #GCA #Rheumatology ... Ophthalmology #Diagnosis ... #Algorithm
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... disease (SVC/IVC occlusion ... Behcet syndrome (Clinical ... ) Differential Diagnosis ... signs #symptoms #rheumatology
When to look for clonal/neoplastic hypereosinophilia (HEo)? - Exclusion of frequent causes (Drug-induced HEo, helminthiasis, cancer,
- Exclusion of frequent ... ) - Clinical symptoms ... hypereosinophilia #HEON #Diagnosis ... #Signs #Hematology
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