12 results
Causes of Hyponatremia - Differential Diagnosis Algorithm
Hypovolemia, UNa > 20: 
 • Renal losses, Diuretic excess,
Causes of Hyponatremia ... UNa > 20: • Renal ... losses, Diuretic ... , Osmotic diuresis ... #Causes #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Causes of Hypokalemia
Transcellular Shifts:
 - Alkalosis, Increased plasma insulin (treatment of diabetic ketoacidosis), ß-Adrenergic agonists, Hypokalemic
plasma insulin (treatment ... Villous adenoma Renal ... chewing tobacco, Renal ... use), Gitelman's ... differential #diagnosis #nephrology
Hypokalemia - Differential Diagnosis Algorithm
Extra-renal Losses:
 • Normal Acid-Base: Low intake
 • Metabolic acidosis: Gl tract
Extra-renal Losses ... loss (Diarrhea) Renal ... Loop and thiazide diuretics ... , Gitelman syndrom ... #low #nephrology
Diuretics and Agents Regulating Renal Excretion

Carbonic Anhydrase Inhibitors (Acetazolamide, Dichlorphenamide)
 • Glaucoma
 • Epilepsy
 • Altitude
Regulating Renal ... alkalosis • Familial ... Inhibitors of Renal ... Renal #Excretion ... #Diuresis #Nephrology
Causes of Metabolic Alkalosis - Differential Diagnosis Algorithm
GI Losses - Gastric
 • Vomiting
 • NG suction
GI
Causes of Metabolic ... Chloridorrhea Renal ... • Penicillins Renal ... tubular transport • Diuretics ... MetabolicAlkalosis #NonGap #Nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Low Cl intake, Diuretics ... High Urine Cl-: Diuretics ... , Gitelman Syndrome ... hyperaldosteronism • High PRA: Renal ... #Nephrology #Causes
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
with thiazide diuretic ... • Hypokalemia (renal ... Surreptitious diuretic ... , Renal tubular ... #nephrology #management
Causes of Metabolic Alkalosis: Differential Diagnosis
ECF volume contracted: urine chloride concentration <20 meq/L
 • Gastric alkalosis:
Causes of Metabolic ... after renal tubule ... diuretic effect ... generally indicates a renal ... #nephrology