17 results
diagnosis management workup algorithm classification leukemia mds monoclonal myelodysplastic anemia aplastic apml arthritis cancer causes chronic clinical cll differentiation disorders
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
Myelodysplastic Syndrome ... abnormal) -plastic (shape ... • Bone marrow ... Management #treatment #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Warm AIHA • Bone ... • Richter’s Syndrome ... leukemia • Sezary syndrome ... diagnosis #workup #oncology ... #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
hypercellular bone ... blood count with differential ... blood smear • Bone ... #diagnosis #hematology ... #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or on bone ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework HEMATOLOGIC ... neutrophil count < 500 cells ... sustained over a one-hour ... #differential #
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
g/dl LLN B - Bony ... marrow plasma cell ... plasmacytoma, POEMs syndrome ... MGUS #diagnosis #hematology ... #oncology
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Lymphoproliferative Disorders - Differential ... Amy Chung, MD, MSc ... Classification #pathophysiology ... #Hematology #Diagnosis ... #NonHodgkin #differential
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
= Hypocellular bone ... Constitutional Syndromes ... • Suggested by bone ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... initiation • Differential ... diagnosis #management #hematology ... #oncology
Causes of Knee Effusions - Differential Diagnosis Framework Knee Effusion Red Flags: 1. Fever/Chills/Joint pain/Night sweats/Weight loss - DDX: -
Knee Effusions - Differential ... sarcoma - Giant cell ... - Aneurysmal bone ... therapy - Sickle cell ... #diagnosis #msk
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