18 results
Sarcoidosis 
Non-caseating granulomas (Composed of T-helper & inflammatory cells) 
Clinical:
 • Disease fatal in 10% of
Sarcoidosis Non-caseating ... fatal in 10% of pts ... Constitutional: Fever ... #Diagnosis #Symptoms ... #Signs #Pulmonary
Sarcoidosis
Stage 1 - Bilateral LAD without involvement of lung parenchyma
Stage 2 - Bilateral LAD with involvement
Sarcoidosis Stage ... gland sweling, fever ... @AnnKumfer #Sarcoidosis ... Stages #Staging #Signs ... #Symptoms #Summary
Common organ involvements and symptoms in Sarcoidosis
Lung 89-99% - Cough, dyspnoea, wheezing and stridor
Skin 16-32% -
in Sarcoidosis ... Lung 89-99% - Cough ... and syncope #Sarcoidosis ... #diagnosis #signs ... #symptoms
Management of patients with known or suspected malignant pleural effusion (MPE) - An Official ATS/STS/STR Clinical
goals of assessing lung ... there are any signs ... /symptoms of worsening ... Effusions #MPE #Algorithm ... #Management #ATS
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... granulomas within the lungs ... at the time of ... #Diagnosis #Management ... #Signs #Symptoms
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... and symptoms: ... cyclosporine A, ATG ... if neutropenic fever ... Anemia #diagnosis #management
Primary Adrenal Insufficiency
Addison's Disease - Damage of the adrenal glands with lack of cortisol, androgens and
Adrenals: • Lung ... vomiting • Fatigue Signs ... Cortisol Deficiency: Signs ... Reduced libido • Signs ... endocrinology #diagnosis #signs
Heart failure with Reduced Ejection Fraction (HFrEF)
Clinical Presentation
1. Typical symptoms: dyspnea, orthopnea paroxysmal noctumal dyspnea, fatigue,
More Specific Signs ... Less Specific Signs ... Chest x-ray: signs ... acute HF → no signs ... heartfailure #diagnosis #management
Post-Transplantation Lymphoproliferative Disorders (PTLD)
Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
higher incidence in lung ... >heart>liver>kidney ... Conditioning regimen Signs ... EBV viral load, signs ... oncology #diagnosis #management
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... - 80% have fever ... - ACS, AKI, ... WBC >100k, + lab signs ... TLS #diagnosis #management