7751 results
REBEL Review 79: Treatment of Hemophilia 

Walkina Out of Pt Room, You Should Know... 
1. Type
Factor Activity ... Type of Factor ... ) Units of Factor ... #factor9 #factorviii ... #factorix
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Differential Diagnosis ... could be multiple factors ... Decreased factor ... Factor consumption ... Prolonged #Causes #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
Hemophilia - Diagnosis ... and Management Diagnosis ... von Willebrand factor ... • Confirm the diagnosis ... #Hemophilia #Diagnosis
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Patient has a factor ... Patient has a factor ... Mixing #Study #diagnosis
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
- Differential Diagnosis ... a coagulation factor ... Von Willebrand factor ... Von Willebrand factor ... #Differential #Diagnosis
Posterior Reversible Encephalopathy Syndrome (PRES) - Diagnosis
Clinical Features:
 • Altered mental status (Either lethargy, confusion, or
Syndrome (PRES) - Diagnosis ... blindness) Risk Factors ... Autoimmune disease Diagnosis ... : Risk Factor + ... Encephalopathy #Syndrome #Diagnosis
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Contact pathway factors ... Decreased factor ... Factor consumption ... Factor X deficiency ... Prolonged #Causes #diagnosis
Blood Product Components, Contents, Volume and Shelf Life

Whole blood (autologous or directed donations) - RBC and
Factors V and VIII ... all coagulation factors ... least 80 units of factor ... von Willebrand factor ... , factor XIII, fibronectin
On the INR of FFP - why transfusing for INR < 1.7 is futile

FFP replaces a
of coagulation factors ... 30% coagulation factors ... fixed increase in factor