569 results
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
could be multiple factors ... Causes include : ... Pre-analytical cause ... Decreased factor ... aPTT #Prolonged #Causes
Hemostasis Physiology

The blood's response to blood vessel injury can be viewed as four interrelated steps. 
Roman
to coagulation factors ... PF-3, platelet factor ... #Hemostasis #Pathophysiology
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Findings Risk factor ... Alzheimer's (99% of cases ... E4 allele Risk factors ... Alzheimer's (1% of cases ... AlzheimersDisease #Dementia #pathophysiology
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... Pre-analytical cause ... Decreased factor ... Factor consumption ... aPTT #Prolonged #Causes
Jaundice - Pathophysiology and Causes

- Amy Chung, MD, MSc @AmyChung 

#Jaundice #Pathophysiology #Differential #Unconjugated #Causes #Diagnosis
Jaundice - Pathophysiology ... and Causes - ... #Jaundice #Pathophysiology ... #Unconjugated #Causes
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Acquired Risk Factors ... Thrombophilia: - Factor ... cardiovascular risk factors ... coagulation and other causes ... Venous #Arterial #pathophysiology
Mixing Study
 • Clotting tests can be abnormal due to either a clotting factor deficiency, or
either a clotting factor ... inhibitor of normal factor ... Patient has a factor ... Patient has a factor ... diagnosis #hematology #pathophysiology
Causes and Pathophysiology of Hypertension

#Causes #Pathophysiology #Hypertension #Primary #Essential #Secondary #Differential

** GrepMed Recommended Text: Guyton and
Causes and Pathophysiology ... Hypertension #Causes ... #Pathophysiology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Consumption of Clotting Factors ... Reduced levels of factors ... protein C and S Pathophysiology ... Treat primary cause ... Coagulation #diagnosis #causes
Congestive Heart Failure - Causes, Pathophysiology and Differential Diagnosis
 • Dilated Cardiomyopathy 
 • Hypertrophic Cardiomyopathy
Heart Failure - Causes ... , Pathophysiology ... • Other HFpEF Causes ... #HeartFailure #Causes ... #Pathophysiology