19 results
Causes of Abnormal PT and/or aPTT
Prolonged Prothrombin Time (PT)
1. Acquired deficiency of FVII
Causes of Abnormal ... PT and/or aPTT ... typically prolong aPTT ... Pre-analytical cause ... #Prolonged #Causes
Differential Diagnosis for a Prolonged PT and aPTT
If the PT and the aPTT are both prolonged,
Prolonged PT and aPTT ... the PT and the aPTT ... Causes include : ... Pre-analytical cause ... , FVII, FIX, FX
How to Evaluate an Abnormal APTT
Step 1: Is the PT or APTT Artifactually Prolonged?
Step 2: Is
Evaluate an Abnormal APTT ... : Is the PT or APTT ... Prolonging the PT or APTT ... to identify the cause ... of Prolonged APTT
Causes of Prolonged PT (INR), Prolonged PTT
 • Prolonged PT (INR), Prolonged PTT
 • Prolonged PT
Causes of Prolonged ... INR), Prolonged PTT ... INR), Prolonged PTT ... (INR), Normal PTT ... Diagnosis #Algorithm #Causes
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)

Prothrombin Time (PT) - Often Elevated in:
 • Vitamin
Thromboplastin Time (PTT ... warfarin) • Factor VII ... Thromboplastin Time (PTT ... thematttsai #PT #PTT
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... levels of factors VII ... Treat primary cause ... INR < 2.3 - APTT ... Coagulation #diagnosis #causes
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Causes of Thrombocytopenia ... practices that could cause ... : INR/PT, aPTT(liver ... patients if the cause ... Differential #Diagnosis #Causes
Causes of AKI in Pregnancy - Differential Diagnosis
Creatinine - Platelets - Transaminases - LDH - PT/PTT
Causes of AKI in ... Transaminases - LDH - PT/PTT ... Differential #Diagnosis #Causes
Algorithm for managing FVII deficiency.

*Mild bleeding history includes minor epistaxis, menorrhagia, gastrointestinal bleeding, joint and soft
Algorithm for managing FVII ... #FVII #deficiency ... #FactorVII #Factor7
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework

== Quantitative or Qualitative defect in
NORMAL PT/NORMAL PTT ... evaluation of factor VII ... Inherited: • Factor VII ... the PT and the PTT ... discern these causes