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1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
Galactomannan Testing Sensitivity ... Specificity and False ... BAL samples • False ... in BAL does not differentiate ... mold-active AF • False
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
dermatidis • Sensitivity ... breakthrough IFI in HM • False ... : Mucorales • Sensitivity ... BAL GM does not differentiate ... recipients, CGD pts • False
Sensitivity Specificity False-Positive False-Negative Contingency Table / confusion matrix Sensitivity refers to the test's ability to correctly
Sensitivity Specificity ... False-Positive ... False-Negative Contingency ... confusion matrix Sensitivity ... #Sensitivity #Specificity
The test characteristics of the heterophile antibody (AKA the monospot test) are not perfect and can
can lead to both false ... positive and false ... Serologies #Titers #Sensitivity
Causes of False Elevation and Reduction in HbA1c == False Elevation == Decreased RBC turnover • Iron, B-12,
Causes of False ... in HbA1c == False ... Transfusions == False ... Transfusions #False ... Diagnosis #DM2 #Differential
Medications that Can Cause False Positives on Drug Tests Urine drug screens (UDSs) are simple to use,
that Can Cause False ... Amphetamine false ... Cannabinoid false ... Benzodiazepine false ... #drug #tests #differential
False Positive Lung Point on POCUS Lung-Cardiac Point and Lung-Diaphragm Point These images highlight selected differentials to pleural
False Positive Lung ... highlight selected differentials ... UAlberta_Sono #False ... ultrasound #pulmonary #differential
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 1,3 Beta-D-Glucan and Galactomannan - Pathogens, and Testing Characteristics 1,3 ß-D-glucan: • Most fungi excluding mucor and
and pneumocystis False ... other fungi • False ... Characteristics #Sensitivity
Important Biostatistics and Epidemiology Equations Sensitivity = TP / (TP + FN) = true positives / disease
Epidemiology Equations Sensitivity ... Likelihood Ratio = Sensitivity ... Specificity Sensitivity ... Mnemonic: - Sensitivity ... diagnosis #mnemonic #sensitivity
Summary of Agents Potentially Contributing to False Positives on Urine Drug Screens (UDS) Marijuana Metabolites • dronabinol,
Contributing to False ... (High Rate of False ... NSAlDs resulting in false-positive ... not result in false
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