21 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
(ALT or AST > ALP ... Wilsons, Pregnancy - AFLP ... Wilson's, HH, NAFLD ... 5x ULN - NAFLD ... Burak @kwburak #LFTs
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... Hemochromatosis • NAFLD ... ALT < 5x ULN • NAFLD ... • Others #LFTs
Assessment of Nonalcoholic Steatohepatitis (NASH) Severity in Patients With Nonalcoholic Fatty
#Diagnosis #Pathology #NAFLD #NASH #Fibrosis #Staging
With Nonalcoholic Fatty ... Diagnosis #Pathology #NAFLD
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... in fetal free fatty ... → Intermediate fatty ... iMedEducation #AFLP
Non-alcoholic fatty liver disease algorithm.
 
For those patients with NAFLD or liver disease of unknown aetiology,
Non-alcoholic fatty ... patients with NAFLD ... calculation of a FIB4 or NAFLD ... non-alcoholic fatty ... disease; NFS, NAFLD
Thrombocytopenia and Pregnancy - TTP/HUS, HELLP Syndrome and Acute Fatty Liver of Pregnancy (AFLP)
Three syndromes in
Syndrome and Acute Fatty ... of Pregnancy (AFLP ... plasma exchange 3) Fatty ... TTPHUS #HELLP #AFLP
Liver Function Test (LFTs) Elevation
AST - Cardiac and skeletal muscle, kidney, brain
ALT - More specific for
Function Test (LFTs ... for the liver ALP ... Transaminase, ALP ... / ULN ALT) / (ALP ... #FunctionTest #LFTs
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework
Mild (<100-500): 
 • NAFLD
 • Cirrhosis
 •
Function Tests (LFTs ... 100-500): • NAFLD ... Function #Tests #LFTs
Histologic Features and Prevalence of Nonalcoholic Steatohepatitis (NASH). NASH is a potentially progressive type of nonalcoholic
of nonalcoholic fatty ... liver disease (NAFLD ... Epidemiology #NASH #NAFLD
Pathogenesis of Nonalcoholic Steatohepatitis. Various factors, including inflammation, hyperinsulinemia or insulin resistance, and altered lipid homeostasis,
to develop in fatty ... #GI #IM #NASH #NAFLD